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1

Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease-modifying antirheumatic drugs: The tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study

Mark C. Genovese, James D. McKay, Evgeny L. Nasonov, Eduardo F. Mysler, Nilzio A. da Silva, Emma Alecock, Thasia Woodworth, Juan J. Gomez-Reino

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 148 KB

english, 2008

2

Biosimilars in rheumatology: a view from Latin America

Mysler, Eduardo, Scheinberg, Morton

Journal:

Clinical Rheumatology

Year:

2012

Language:

english

File:

PDF, 66 KB

english, 2012

3

Biopharmaceuticals for rheumatic diseases in Latin America, Europe, Russia, and India: Innovators, biosimilars, and intended copies

Castañeda-Hernández, Gilberto, Szekanecz, Zoltan, Mysler, Eduardo, Azevedo, Valderilio F., Guzman, Renato, Gutierrez, Miguel, Rodríguez, Wilfredo, Karateev, Dmitry

Journal:

Joint Bone Spine

Year:

2014

Language:

english

File:

PDF, 580 KB

english, 2014

4

Evaluating upadacitinib for the treatment of rheumatoid arthritis

Mysler, Eduardo, Lizarraga, Ana

Journal:

Expert Opinion on Pharmacotherapy

Year:

2020

File:

PDF, 1.59 MB

2020

5

Ciprofloxacin reactions mimicking lupus flares

Eduardo Mysler, Stephen A. Paget, Robert Kimberly

Journal:

Arthritis & Rheumatism

Year:

1994

Language:

english

File:

PDF, 234 KB

english, 1994

6

Levels of soluble fas/APO-1 /CD95 in systemic lupus erythematosus and juvenile rheumatoid arthritis

Eckart Knipping, Peter H. Krammer, Karen B. Onel, Thomas J. A. Lehman, Eduardo Mysler, Keith B. Elkon

Journal:

Arthritis & Rheumatism

Year:

1995

Language:

english

File:

PDF, 304 KB

english, 1995

7

Subcutaneous abatacept versus intravenous abatacept: A phase IIIb noninferiority study in patients with an inadequate response to methotrexate

M. C. Genovese, A. Covarrubias, G. Leon, E. Mysler, M. Keiserman, R. Valente, P. Nash, J. A. Simon-Campos, W. Porawska, J. Box, C. Legerton III, E. Nasonov, P. Durez, R. Aranda, R. Pappu, I. Delaet, J

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 415 KB

english, 2011

8

Prevalence of positive ppd in a cohort of rheumatoid arthritis patients

Maria Natalia Tamborenea, Guillermo Tate, Eduardo Mysler, Jose Debonis, Adrian Schijedman

Journal:

Rheumatology International

Year:

2010

Language:

english

File:

PDF, 199 KB

english, 2010

9

Lumiracoxib (Prexige®): a new selective cox-2 inhibitor

Journal:

International Journal of Clinical Practice

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

10

P362 LUMIRACOXIB SHOWS COMPARABLE EFFICACY AND A FAVOURABLE BLOOD PRESSURE PROFILE COMPARED TO INDOMETHACIN FOR THE TREATMENT OF ACUTE FLARES OF GOUT

E.F. Mysler, R.E. Willburger, S. Litschig, G. Krammer, G.A. Tate

Journal:

Osteoarthritis and Cartilage

Year:

2006

Language:

english

File:

PDF, 49 KB

english, 2006

11

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial

Thomas J Schnitzer, Gerd R Burmester, Eduardo Mysler, Marc C Hochberg, Michael Doherty, Elena Ehrsam, Xavier Gitton, Gerhard Krammer, Bernhard Mellein, Patrice Matchaba, Alberto Gimona, Christopher J

Journal:

Year:

2004

Language:

english

File:

PDF, 126 KB

english, 2004

12

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial

Michael E Farkouh, Howard Kirshner, Robert A Harrington, Sean Ruland, Freek WA Verheugt, Thomas J Schnitzer, Gerd R Burmester, Eduardo Mysler, Marc C Hochberg, Michael Doherty, Elena Ehrsam, Xavier Gi

Journal:

Year:

2004

Language:

english

File:

PDF, 118 KB

english, 2004

13

Canakinumab Reduces The Risk Of Acute Gouty Arthritis Flares During Initiation Of Allopurinol Therapy: Results Of A Double-blind, Randomised Study

Schlesinger, N., Mysler, E., Lin, H., DeMeulenmeester, M., Rovensky, J., Arulmani, U., Balfour, A., Krammer, G., Sallstig, P., So, A.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 44 KB

english, 2011

14

Influence of corticosteroids on C-reactive protein in patients with rheumatoid arthritis

E Mysler, C Psioni, P Tate, G Tate

Journal:

Arthritis Research & Therapy

Year:

2004

Language:

english

File:

PDF, 391 KB

english, 2004

15

Efficacy and Safety of Ocrelizumab in Active Proliferative Lupus Nephritis: Results From a Randomized, Double-Blind, Phase III Study

Mysler, Eduardo F., Spindler, Alberto J., Guzman, Renato, Bijl, Marc, Jayne, David, Furie, Richard A., Houssiau, Frédéric A., Drappa, Jorn, Close, David, Maciuca, Romeo, Rao, Kajal, Shahdad, Saba, Bru

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 148 KB

english, 2013

16

Work instability in rheumatoid arthritis patients from Argentina: prevalence and associated factors

Tamborenea, Maria N., Pisoni, Cecilia, Toloza, Sergio, Mysler, Eduardo, Tate, Guillermo, Pereira, Dora, García Carrasco, M., Quintero, J., Cappuccio, A., Granel, A., Lazaro, M., Arturi, Pablo, Citera,

Journal:

Rheumatology International

Year:

2015

Language:

english

File:

PDF, 211 KB

english, 2015

17

A randomised, double-blind, parallel-group study of the safety and efficacy of subcutaneous tocilizumab versus intravenous tocilizumab in combination with traditional disease-modifying antirheumatic drugs in patients with moderate to severe rheumatoid arthritis (SUMMACTA study)

Burmester, G. R., Rubbert-Roth, A., Cantagrel, A., Hall, S., Leszczynski, P., Feldman, D., Rangaraj, M. J., Roane, G., Ludivico, C., Lu, P., Rowell, L., Bao, M., Mysler, E. F.

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

18

The effect of antidrug antibodies on the sustainable efficacy of biologic therapies in rheumatoid arthritis: practical consequences

Keiserman, Mauro, Codreanu, Catalin, Handa, Rohini, Xibillé-Friedmann, Daniel, Mysler, Eduardo, Briceño, Francisco, Akar, Servet

Journal:

Expert Review of Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 303 KB

english, 2014

19

Biothérapies en rhumatologie en Amérique Latine, en Europe, en Russie et en Inde : produits innovants, biosimilaires et prétendues copies

Castañeda-Hernández, Gilberto, Szekanecz, Zoltan, Mysler, Eduardo, Azevedo, Valderilio F., Guzman, Renato, Gutierre, Miguel, Rodríguez, Wilfredo, Karateev, Dmitry

Journal:

Revue du Rhumatisme

Year:

2015

Language:

french

File:

PDF, 528 KB

french, 2015

20

Biosimilars: Clinical Interpretation and Implications for Drug Development

Mysler, Eduardo

Journal:

Current Rheumatology Reports

Year:

2015

Language:

english

File:

PDF, 751 KB

english, 2015

21

Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis

Appel, G. B., Contreras, G., Dooley, M. A., Ginzler, E. M., Isenberg, D., Jayne, D., Li, L.-S., Mysler, E., Sanchez-Guerrero, J., Solomons, N., Wofsy, D.

Journal:

Journal of the American Society of Nephrology

Year:

2009

Language:

english

File:

PDF, 153 KB

english, 2009

22

A reversible bilateral renal artery stenosis in association with Antiphospholipid Syndrome

Remondino, G I, Mysler, E, Pissano, M N, Furattini, M C, Basta, M C, Presas, J L, Allievi, A

Journal:

Year:

2000

Language:

english

File:

PDF, 162 KB

english, 2000

23

Sifalimumab, a Human Anti-Interferon-α Monoclonal Antibody, in Systemic Lupus Erythematosus: A Phase I Randomized, Controlled, Dose-Escalation Study

Petri, Michelle, Wallace, Daniel J., Spindler, Alberto, Chindalore, Vishala, Kalunian, Kenneth, Mysler, Eduardo, Neuwelt, C. Michael, Robbie, Gabriel, White, Wendy I., Higgs, Brandon W., Yao, Yihong,

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 432 KB

english, 2013

24

Lumiracoxib 400 mg once daily is comparable to indomethacin 50 mg three times daily for the treatment of acute flares of gout

Willburger, R. E., Mysler, E., Derbot, J., Jung, T., Thurston, H., Kreiss, A., Litschig, S., Krammer, G., Tate, G. A.

Journal:

Year:

2007

Language:

english

File:

PDF, 292 KB

english, 2007

25

Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study

Schlesinger, N., Mysler, E., Lin, H.-Y., De Meulemeester, M., Rovensky, J., Arulmani, U., Balfour, A., Krammer, G., Sallstig, P., So, A.

Journal:

Annals of the Rheumatic Diseases

Year:

2011

Language:

english

File:

PDF, 367 KB

english, 2011

26

Catastrophic antiphospholipid syndrome complicating orthotopic liver transplantation

Villamil, A, Sorkin, E, Basta, M C, Mysler, E, Macias, S, Pekolj, J, Ciardullo, M, Eleta, F, de Santibañes, E, Allievi, A, Gadano, A

Journal:

Year:

2003

Language:

english

File:

PDF, 197 KB

english, 2003

27

Subcutaneous Abatacept for the Treatment of Rheumatoid Arthritis: Longterm Data from the ACQUIRE Trial

Genovese, M. C., Tena, C. P., Covarrubias, A., Leon, G., Mysler, E., Keiserman, M., Valente, R., Nash, P., Simon-Campos, J. A., Box, J., Legerton, C. W., Nasonov, E., Durez, P., Delaet, I., Teng, J.,

Journal:

The Journal of Rheumatology

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

28

SAT0244 A Phase Iib Study of the Efficacy and Safety of Subcutaneous Clazakizumab (ANTI-IL-6 Monoclonal Antibody) with or without Methotrexate in Adults with Moderate-To-Severe Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Weinblatt, M., Mease, P., Mysler, E., Takeuchi, T., Drescher, E., Berman, A., Zilberstein, M., Xing, J., Emery, P.

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 180 KB

english, 2014

29

Clinical and regulatory perspectives on biosimilar therapies and intended copies of biologics in rheumatology

Mysler, Eduardo, Pineda, Carlos, Horiuchi, Takahiko, Singh, Ena, Mahgoub, Ehab, Coindreau, Javier, Jacobs, Ira

Journal:

Rheumatology International

Year:

2016

Language:

english

File:

PDF, 607 KB

english, 2016

30

The Efficacy and Safety of Subcutaneous Clazakizumab in Patients With Moderate-to-Severe Rheumatoid Arthritis and an Inadequate Response to Methotrexate: Results From a Multinational, Phase IIb, Randomized, Double-Blind, Placebo/Active-Controlled, Dose-Ra

Weinblatt, Michael E., Mease, Philip, Mysler, Eduardo, Takeuchi, Tsutomu, Drescher, Edit, Berman, Alberto, Xing, Jun, Zilberstein, Moshe, Banerjee, Subhashis, Emery, Paul

Journal:

Arthritis & Rheumatology

Year:

2015

Language:

english

File:

PDF, 366 KB

english, 2015

31

Metástasis en la túnica vaginal del testículo derecho de adenocarcinoma colorrectal

Causa Andrieu, P., Coronil, J.R., Tirapegui, S., Ocantos, J., Mysler, D., Isola, M., Gueglio, G.

Journal:

Revista Argentina de Radiología

Year:

2016

File:

PDF, 1.27 MB

2016

32

L’indice de masse corporelle n’a pas d’impact sur la réponse à l’abatacept sous-cutané ou intraveineux chez les patients souffrant de polyarthrite rhumatoïde

D'Agostino, M.A., Alten, R., Mysler, E., Le Bars, M., Ye, J., Murthy, B., Heitzmann, J., Vadanici, R., Ferraccioli, G.

Journal:

Revue du Rhumatisme

Year:

2016

Language:

french

File:

PDF, 653 KB

french, 2016

33

Tolérance et efficacité à 5 ans d’abatacept sous-cutané chez des patients présentant une PR modérée à sévère et une réponse inadéquate au MTX : extension à long terme de l’étude de phase III, randomisée et en double aveugle ACQUIRE

Durez, P., Genovese, M.C., Tena, C. Pacheco, Covarrubias, A., Leon, G., Mysler, E., Keiserman, M., Valente, R., Nash, P., Simon-Campos, J.A., Box, J., Legerton Iii, C.W., Nasonov, E., Elegbe, A., Wong

Journal:

Revue du Rhumatisme

Year:

2016

Language:

french

File:

PDF, 174 KB

french, 2016

34

A randomised phase IIb study of mavrilimumab, a novel GM–CSF receptor alpha monoclonal antibody, in the treatment of rheumatoid arthritis

Burmester, Gerd R, McInnes, Iain B, Kremer, Joel, Miranda, Pedro, Korkosz, Mariusz, Vencovsky, Jiri, Rubbert-Roth, Andrea, Mysler, Eduardo, Sleeman, Matthew A, Godwood, Alex, Sinibaldi, Dominic, Guo,

Journal:

Annals of the Rheumatic Diseases

Year:

2017

Language:

english

File:

PDF, 1.54 MB

english, 2017

35

OP0034 Efficacy and Safety of Mavrilimumab, A Fully Human Gm–CSFR-Alpha Monoclonal Antibody in Patients with Rheumatoid Arthritis: Primary Results from the Earth Explorer 1 Study

Burmester, G.R., McInnes, I.B., Kremer, J.M., Miranda, P., Korkosz, M., Vencovsky, J., Rubbert-Roth, A., Mysler, E., Sleeman, M.A., Godwood, A., Albulescu, M., Close, D., Weinblatt, M.

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 106 KB

english, 2015

36

Safety of Tofacitinib in the Treatment of Rheumatoid Arthritis in Latin America Compared With the Rest of the World Population

Castañeda, Oswaldo M., Romero, Felix J., Salinas, Ariel, Citera, Gustavo, Mysler, Eduardo, Rillo, Oscar, Radominski, Sebastiao C., Cardiel, Mario H., Jaller, Juan J., Alvarez-Moreno, Carlos, Ponce de

Journal:

JCR Journal of Clinical Rheumatology

Year:

2017

Language:

english

File:

PDF, 781 KB

english, 2017

37

Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-to-head, randomised controlled trial

Fleischmann, Roy, Mysler, Eduardo, Hall, Stephen, Kivitz, Alan J, Moots, Robert J, Luo, Zhen, DeMasi, Ryan, Soma, Koshika, Zhang, Richard, Takiya, Liza, Tatulych, Svitlana, Mojcik, Christopher, Krishn

Journal:

Year:

2017

Language:

english

File:

PDF, 661 KB

english, 2017

38

Switching Between Reference Biologics and Biosimilars for the Treatment of Rheumatology, Gastroenterology, and Dermatology Inflammatory Conditions: Considerations for the Clinician

Moots, Robert, Azevedo, Valderilio, Coindreau, Javier L., Dörner, Thomas, Mahgoub, Ehab, Mysler, Eduardo, Scheinberg, Morton, Marshall, Lisa

Journal:

Current Rheumatology Reports

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

39

Body mass index and clinical response to intravenous or subcutaneous abatacept in patients with rheumatoid arthritis

D’Agostino, Maria-Antonietta, Alten, Rieke, Mysler, Eduardo, Le Bars, Manuela, Ye, June, Murthy, Bindu, Heitzmann, Julia, Vadanici, Radu, Ferraccioli, Gianfranco

Journal:

Clinical Rheumatology

Year:

2017

Language:

english

File:

PDF, 574 KB

english, 2017

40

Treatment Patterns and Satisfaction For Rheumatoid Arthritis Patients In Latin America Undergoing Advanced Therapy

Papadimitropoulos, M, Mysler, E, Garcia, EG, Lobosco, S, Botello, BS, Leonardi Reyes, F, Haynes, G

Journal:

Value in Health

Year:

2017

Language:

english

File:

PDF, 59 KB

english, 2017

41

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, 14–17 June, 2017 - ()] Abstracts Accepted for Publication - AB0379 Efficacy outcomes for originator tnf inhibitors and biosimilars in rheumatoid arthritis and psoriasis trials: a systematic literature review

Moots, R, Curiale, C, Petersel, D, Rolland, C, Jones, H, Singh, E, Mysler, E

Language:

english

File:

PDF, 222 KB

english

42

Etanercept for the treatment of rheumatoid arthritis

Zhao, Sizheng, Mysler, Eduardo, Moots, Robert J

Journal:

Year:

2018

Language:

english

File:

PDF, 832 KB

english, 2018

43

Longterm Safety and Efficacy of Subcutaneous Abatacept in Patients with Rheumatoid Arthritis: 5-year Results from a Phase IIIb Trial

Genovese, Mark C., Pacheco-Tena, César, Covarrubias, Arturo, Leon, Gustavo, Mysler, Eduardo, Keiserman, Mauro, Valente, Robert M., Nash, Peter, Simon-Campos, J. Abraham, Box, Jane, Legerton, Clarence

Journal:

The Journal of Rheumatology

Year:

2018

Language:

english

File:

PDF, 802 KB

english, 2018

44

O22. Efficacy and Safety of Subcutaneous Versus Intravenous Tocilizumab In Combination with Traditional Dmards in Patients with Rheumatoid Arthritis: 49 Week Summacta Data

Burmester, Gerd R., Rubbert-Roth, Andrea, Cantagrel, Alain, Hall, Stephen, Leszczyński, Piotr, Feldman, Daniel, Rangaraj, Madura J., Roane, Georgia, Ludivico, Charles, Mysler, Eduardo F., Wells, Chris

Journal:

Year:

2014

Language:

english

File:

PDF, 30 KB

english, 2014

45

FRI0316 The Efficacy and Safety of Subcutaneous Tocilizumab versus Intravenous Tocilizumab in Combination with Traditional DMARDS in Patients with RA at Week 97 (SUMMACTA)

Burmester, G., Rubbert-Roth, A., Cantagrel, A., Hall, S., Leszczynski, P., Feldman, D., Rangaraj, M.J., Roane, G., Ludivico, C., Mysler, E., Bennett, M.J., Rowell, L., Bao, M.

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 169 KB

english, 2014

46

THU0149 The 54-Week Results of Interferon-γ Release Assay in A Phase III Study Comparing SB2, An Infliximab Biosimilar, To Infliximab Reference Product in Patients with Rheumatoid Arthritis: Table 1.

Durez, P., Mysler, E., Smolen, J.S., Choe, J.-Y., Choi, J., Rho, Y.H.

Journal:

Annals of the Rheumatic Diseases

Year:

2016

Language:

english

File:

PDF, 198 KB

english, 2016

47

FRI0227 Five-Year Safety and Efficacy of Subcutaneous Abatacept in Patients with Moderate To Severely Active RA and An Inadequate Response To MTX: Long-Term Extension of The Phase III, Double-Blind, Randomized Acquire Study:

Genovese, M.C., Pacheco Tena, C., Covarrubias, A., Leon, G., Mysler, E., Keiserman, M., Valente, R., Nash, P., Simon-Campos, J.A., Box, J., Legerton, C.W., Nasonov, E., Durez, P., Elegbe, A., Wong, R.

Journal:

Annals of the Rheumatic Diseases

Year:

2016

Language:

english

File:

PDF, 108 KB

english, 2016

48

SAT0105 Summacta: A Randomized, Double-Blind, Parallel Group Study of the Safety and Efficacy Of Tocilizumab SC Versus Tocilizumab IV, in Combination with Traditional Dmards in Patients With Moderate to Severe Ra

Burmester, G. R., Rubbert-Roth, A., Cantagrel, A., Hall, S., Leszczynski, P., Feldman, D., Rangaraj, M. J., Roane, G., Ludivico, C., Mysler, E., Rowell, L., Vranic, I.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 276 KB

english, 2013

49

FRI0123 Biologic monotherapy (BMT) as a treatment pattern in ra patients in a developing country.

Mysler, E., Alvarellos, A., Borgia, A., Eimon, A., García Salinas, R., Najún Dubos, L., Re, L., Siri, D., Solé, J. P., Sommerfleck, F., Velasco Zamora, J., Wiederhold, C.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 254 KB

english, 2013

50

THU0246 Subcutaneous Abatacept: Long-Term Data From the Acquire Trial

Alten, R., Pacheco-Tena, C., Covarrubias, A., Leon, G., Mysler, E., Keiserman, M., Valente, R., Nash, P., Simon-Campos, J., Box, J., Legerton, C., Nasonov, E., Durez, P., Delaet, I., Genovese, M.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 247 KB

english, 2013